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AMPA receptor modulator-1

CAS No. 2036074-41-4

AMPA receptor modulator-1( —— )

Catalog No. M32776 CAS No. 2036074-41-4

AMPA receptor modulator-1 can be activated by glutamate, thereby modulating ion channels.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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2MG 178 Get Quote
5MG 255 Get Quote
10MG 374 Get Quote
25MG 545 Get Quote
50MG 762 Get Quote
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Biological Information

  • Product Name
    AMPA receptor modulator-1
  • Note
    Research use only, not for human use.
  • Brief Description
    AMPA receptor modulator-1 can be activated by glutamate, thereby modulating ion channels.
  • Description
    AMPA receptor modulator-1 is a potent, orally active and selective AMPAR regulatory protein TARP γ-8 negative modulator with a pIC50 of 9.7, more selective over GluA1/γ-2 (pIC50=5).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    iGluR
  • Recptor
    iGluR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2036074-41-4
  • Formula Weight
    341.71
  • Molecular Formula
    C16H11ClF3NO2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O(C(F)(F)F)C1=C(C=2C=C3C(=C(C)C2)NC(=O)C3)C(Cl)=CC=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Ravula S, et al. Lead Optimization of 5-Aryl Benzimidazolone- and Oxindole-Based AMPA Receptor Modulators Selective for TARP γ-8. ACS Med Chem Lett. 2018 Jul 13;9(8):821-826.?
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